Mautic often requires cron jobs to be triggered manually. The package comes with a a default cronjob template. This is saved in /app/data/crontab.system.

You can change the schedule and arguments of the cronjobs as desired using the File manager. Be sure to restart the app after making any changes.

To run a cron job manuall, open a Web terminal and run the job manually like so:
sudo -E -u www-data php /app/code/bin/console mautic:segments:update